Promoting the Formation of Tetramolecular G-quadruplexes under Freezing Condition
Bioorganic & medicinal chemistry letters(2012)
摘要
In the study, we demonstrated that freezing was able to facilitate the short DNA strand T(4)G(4) to self-assemble into a tetramolecular G-quadruplex with a low DNA concentration in the absence of any ligand, providing a fast approach to configure intermolecular G-quadruplexes. The fast formation of intermolecular G-quadruplexes may offer a convenient tool.
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关键词
Freezing,Tetramolecular G-quadruplexes,Promotion,Self-assembling
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