甲状腺激素水平变化与抑郁症的关系
Asia-Pacific Traditional Medicine(2010)
Abstract
目的:探讨抑郁症患者的甲状腺激素水平与其发病的关系。方法:按性别、年龄1∶1匹配选取序贯就诊的患者和体检健康者各28例,采用放射免疫法测定患者组治疗前后和对照组血清T3、T4、rT3和TSH浓度。结果:患者组治疗前、后血清T4水平为(135.4±22.0)μg/L和(113.1±20.3)μg/L,明显高于对照组(103.9±10.3)μg/L,治疗后T4明显下降;治疗前T4与HAMD评分呈显著性正相关(r=0.41,P<0.05)。结论:抑郁症T4升高继发于情绪障碍,可以根据治疗前血清T4水平预测患者的抑郁症严重度。
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