重型再生障碍性贫血CD4~+CD25~+调节性T细胞的研究
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine(2007)
Abstract
目的:应用流式细胞术检测SAA患者外周血CD4+CD25+T细胞、CD4+CD25highT细胞的数量。结果:10例初治SAA患者外周血CD4+CD25+T细胞占CD4+T细胞的(6.23±1.82)%,明显低于正常对照组(9.20+2.95)%(P<0.01),CD4+CD25highT细胞比例为(1.02±0.11)%,亦明显低于正常对照组(1.43±0.41)%;10例造血恢复SAA患者CD4+CD25+T细胞和CD4CD25highT细胞比例分别为(8.92±1.22)%和(1.41±0.64)%,与正常对照组无明显差异(P>0.01)。认为+CD4+CD25+、CD4+CD25highT细胞水平与SAA密切相关。
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