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Erratum to “Ketene aminal-based lactam derivatives as a novel class of orally active FXa inhibitors” [Bioorg. Med. Chem. Lett. 15 (2005) 5453–5458]

Yan Shi,Jing Zhang,Philip D. Stein,Mengxiao Shi,Stephen P. O’Connor,Sharon N. Bisaha,Chi Li,Karnail S. Atwal,Gregory S. Bisacchi,Doree Sitkoff,Andrew T. Pudzianowski,Eddie C. Liu,Karen S. Hartl,Steven M. Seiler,Sonia Youssef,Thomas E. Steinbacher,William A. Schumacher,Alan R. Rendina,Jeffrey M. Bozarth,Tara L. Peterson,Ge Zhang,Robert Zahler

Bioorganic & Medicinal Chemistry Letters（2006）

Cited 7|Views68
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Abstract
N,N'-Disubstituted ketene aminals are good bioisosteres of thiourea functional groups. We report the design and synthesis of a novel class of ketene aminal-based lactam derivatives as potent and orally active FXa inhibitors.
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Key words
lactam derivatives,inhibitors,aminal-based
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