Stability of liposomes in circulation is markedly enhanced by structural modification of their phospholipid component
FEBS Letters(1983)
摘要
Replacement of the C-2 ester group in phosphatidylcholine by the carbamyloxy function rendered its liposomes completely stable and longer living in the circulation of rats.
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关键词
Drug delivery,Modified liposomes,Plasma-induced leakage,Lipid transfer,Blood clearance,Tissue uptake
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