Hypertrophic cardiomyopathy, ten years' experience.
Irish journal of medical science(1987)
Abstract
Summary A RETROSPECTIVE study was performed of patients who were diagnosed as having hypertrophic cardiomyopathy by left ventricular
angiography in order to assess the incidence, the clinical and haemodynamic features and prognosis of this condition. The
records of the cardiac catheter laboratory were reviewed for the ten year period from May 1975 to June 1985 to obtain haemodynamic
and angiographic findings at diagnosis. Clinical features were obtained from the hospital records. To assess the prognosis,
the clinical status of all patients, where possible, was reviewed in June 1985. During the ten year period 64 patients were
diagnosed as having hypertrophic cardiomyopathy which was approximately 1% of all cardiac catheterizations. At diagnosis 22%
of patients were asymptomatic and the commonest symptoms were chest pain or dyspnoea. Only 12% of patients had a family history
of hypertrophic cardiomyopathy or sudden death. A systolic murmur was the most common abnormality on physical examination.
Although evidence of left ventricular hypertrophy demonstrated by ECG was very common, only 13% of patients have evidence
of an intraventricular pressure gradient. Of the 52 patients (81% of total) available for follow-up in June 1985, seven (13%)
had died since diagnosis, all suddenly. The patients who died were significantly younger than the survivors and evidence of
left ventricular hypertrophy was also more common in those who died. Our study confirms that although hypertrophie cardiomyopathy
is uncommon, it carries a definite mortality. Thus definitive diagnosis of this condition is important especially as there
is now evidence to suggest that the prognosis may be improved by treatment with amiodarone.
MoreTranslated text
Key words
physical examination,family history,pressure gradient,retrospective study
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined