Relationship Between Calcium Metabolism And Benign Paroxysmal Positional Vertigo In North Sardinia Population

BACKGROUND: Benign paroxysmal positional vertigo (BPPV) has a reported recurrence ranging from 26.8 to 50%. Osteoporosis and Vitamin D deficiency seems to have an impact on recurrence of BPPV.OBJECTIVE: to evaluate the impact of osteoporosis and Vitamin D deficiency on recurrence of BPPV.METHODS: 73 consecutive patients were divided in two groups according to the presence (group 1) or absence (group 0) of a recurrent episode. BMD, femoral and lumbar T-scores and Vitamin D levels were recorded. Statistical analysis was performed to investigate correlations.RESULTS: patients in group 1 had statistically significant lower values of both femoral (-1,62 +/- 1,06 vs. -0,53 +/- 1,51; p = 0,001), lumbar T-score (-2,10 +/- 1,19 vs -0, 53 +/- 1.51, p = 0.001) and Vitamin D (19.53 +/- 15.33). The values of femoral T-score and Vitamin D could be combined in a model able to properly classify 65.8% of the cases (p = 0.002) as isolated or recurrent BPPV, with high accuracy (AUC 0.710 [0.590 - 0.830]).CONCLUSION: present data show a probable correlation between osteoporosis and Vitamin D with recurrent BPPV.