Identification of New Cryoprotective Agents for Cultured Mammalian-Cells
In vitro(1983)
摘要
Thirty-one compounds have been identified that act as cryoprotective agents for cultured mammalian cells. Eight compounds were comparable to dimethylsulfoxide (DMSO) in cryprotective effectivenes. Many of the cryoprotective compounds studied also (a) promote cell fusion and (b) induce cell differentiation in erythroleukemia and other cell systems. Thus previously unrecognized effects on the differentiated state of cells may occur when cells are treated with cryoprotective agents.
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关键词
cryoprotective agents,cell fusion,dimethylsulfoxide,cell differentiation,erythroleukemia
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