Massive Elevation of Procalcitonin in a Patient With Acquired Immunodeficiency Syndrome Due to Multicentric Castleman Disease:

A patient with human immunodeficiency virus having lymphadenoma, hepatosplenomegaly, fever, and weight loss was referred to the hospital. Because of a massive rise of procalcitonin, an extensive antibiotic therapy was initiated which, however, did not result in any clinical improvement. Tissue diagnosis revealed a multicentric Castleman disease. After consecutive chemotherapy, procalcitonin levels decreased by less than 3 log suggesting a causative role of multicentric Castleman disease.