The Influence of Percutaneous Laser Disc Decompression on The Level of Serum 6-keto-PGE1α of Discogenic Back Pain Patients

Objective To study the influence of percutaneous laser disc decompression on the level of serum 6-keto-PGE1α of discogenic back pain Patients,to offer a theoretical basis of clinical application and promotion.Methods 30 cases of DLBP were divided into 2 groups:pretreatment and post-treament,serum 6-keto-PGE1αconcentration were measured before therapy and after therapy 1 week.30 volunteer peoples who were health blood donor as the control group and measured serum 6-keto-PGE1α.The visual analogue scale(VAS) and the operation evaluation criteria of lumbago and backache of Chinese Medical Association Spine Group was taken to value the therapeutic effect.Results the concentration of serum 6-keto-PGE1αin Group A(54.745 0±12.663) pg/mL is much higher than in group B(47.307 5±5.316) pg/mL and C(45.338 0±7.909) pg/mL,the difference is significant(P0.05).By pairedT analysis,the difference between group A,B(before therapy and after therapy) was significant.The VAS score in group B(1.0±1.8) was much lower than that of group A,there were significant differences(P0.01) between them.The assessment of function was excellent in 21cases,good in 7 cases,fair in 1 cases,bad in 1 cases.The excellent and good rate was 93.3%.Conclusion PGE2 has been proved high compact with the mechanism of PLDD in treatment of DLBP.