Comparative study of accelerated solvent extraction and supercritical fluid extraction of total phenolics and flavonoids from Sideritis raeseri subsp. attica and study of antioxidant activity

The genus Sideritis (Lamiaceae) comprises 8 species and 7 subspecies according to Flora of Greece [1, 2]. Sideritis species are often used in Mediterranean countries as herbal tea, and the common Greek name of these plants is „mountain tea“. Moreover, these plants are used in Mediterranean traditional medicine for their antiinflammatory, antirheumatic, and antimicrobial activities [3, 4]. Over the years, the phytochemistry of the genus Sideritis (Lamiaceae) has been studied and several flavonoid aglycones and glycosides have been identified. It is well known that these natural compounds possess a good antioxidant activity [5].