Quantitative measurement of dural ectasia: associations with clinical and genetic characteristics in Marfan syndrome

Gianfranco Vornetti,Giulio Vara,Maria Chiara Baroni,Elisabetta Mariucci,Andrea Donti,Luigi Cirillo,Stefano Ratti, Elena Cantoni, Greta Venturi,Caterina Tonon,Raffaele Lodi,Luca Spinardi

European Spine Journal（2024）

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摘要

Dural ectasia (DE) may significantly impact Marfan syndrome (MFS) patients’ quality of life due to chronic lower back pain, postural headache and urinary disorders. We aimed to evaluate the association of quantitative measurements of DE, and their evolution over time, with demographic, clinical and genetic characteristics in a cohort of MFS patients. We retrospectively included 88 consecutive patients (39

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关键词

Dural ectasia,Marfan syndrome,Fibrillin-1,Genotype-phenotype,MRI,CT

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