Uveal Melanoma: Molecular and Genetic Mechanisms of Development and Therapeutic Approaches

M. V. Zhilnikova, O. S. Troitskaya, D. D. Novak, V. V. Atamanov,O. A. Koval

Molecular Biology（2024）

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摘要

Uveal melanoma (UM) is a neuroectodermal tumor that results from malignant transformation of melanocytes in the eye uvea, including the iris, the ciliary body, and the choroid. UM accounts for 5

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关键词

uveal melanoma,melanosomes,driver mutations,BAP1,GNAQ/11,tebentafusp,epigenetic targets

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