Sarcopenic obesity is part of obesity paradox in dementia development: evidence from a population-based cohort study

Junhan Zhang,Xiaona Na,Zhihui Li,John S. Ji,Guowei Li,Haibing Yang,Yucheng Yang,Yuefeng Tan,Jian Zhang,Menglu Xi, Donghan Su,Huatang Zeng,Liqun Wu,Ai Zhao

BMC Medicine（2024）

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摘要

Sarcopenic obesity, a clinical and functional condition characterized by the coexistence of obesity and sarcopenia, has not been investigated in relation to dementia risk and its onset. We included 208,867 participants from UK biobank, who aged 60 to 69 years at baseline. Dementia diagnoses were identified using hospital records and death register data. Hazard ratios (HRs) and 95

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Sarcopenic obesity,Obesity,Sarcopenia,Dementia,Onset,Brain structure

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