Supplementary Figure S5 from Early Detection of Molecular Residual Disease and Risk Stratification for Children with Acute Myeloid Leukemia via Circulating Tumor DNA
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摘要
Figure S5. Comparison of PFS stratified by the different timepoint post-treatment residual status either of plasma ctDNA or MFC at (A) C2D1, (B) C3D1 and (C) C4D1 post-treatment. ctDNA neg-MFC neg was defined as the VAF of mutation being negative for ctDNA and MRD being negative for MFC at each timepoint. ctDNA pos-MFC neg was defined as the VAF of mutation >0.01% for ctDNA and MRD being negative for MFC at each timepoint. ctDNA pos-MFC pos was defined as the VAF of mutation >0.01% for ctDNA and immunophenotype ≥10−4 myeloblasts for MFC at each timepoint. MFC, multiparameter flow cytometry; C2D1, Cycle 2 day 1; C3D1, Cycle 3 day 1; C4D1, Cycle 4 day 1
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