Advanced MRI processing for clinical glioma research (PubMed).

Abstract This guide summarizes the state-of-the-art processing software solutions and the repositories/communities for the following advanced MRI methods: DSC; DCE; ASL; diffusion MRI; relaxometry; MRF; MRS; CEST; SWI; QSM; MRE; and task-based and resting-state fMRI. For each of those, after a short introduction about the method and output parameters, the required and recommended image processing steps and quality control measures are described, and we point to further literature for more details. In addition, an overview of openly available software tools that provide these functionalities for MRI processing and exemplify workflows is given. Wherever possible, the readers are guided toward existing inventories, repositories, and communities, which offer not only a collection of these tools, but also more in-depth guidance. Each part concludes with an appraisal of the estimated required expertise and future development needs.