Phenolic Profile with Biological Activities Assessment of Ethanolic and Aqueous Extracts from Ephedra alata
Chemistry Africa(2024)
摘要
Ephedra alata aerial parts are often used in Tunisian traditional medicine, especially patients with cancer. The current paper highlights, for the first time, the pro-apoptotic properties of its aqueous and ethanolic extracts on leukemic, colon and pancreatic cancers. Furthermore, their anti-inflammatory and antioxidant activities were evaluated. Both extracts phenolic profile’s was assessed by HPLC analysis. A total of eight and seven compounds respectively in ethanolic and aqueous extracts, were identified as tyrosol (31.86–50.17
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关键词
Ephedra alata,Antioxidant,Anti-inflammatory,Pro-apoptotic,Flow Cytometry,Hematopoietic Monocytic THP-1,Colon Carcinoma SW-620,Pancreatic Carcinoma AsPC-1
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