Phenolic Profile with Biological Activities Assessment of Ethanolic and Aqueous Extracts from Ephedra alata

Chemistry Africa(2024)

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摘要
Ephedra alata aerial parts are often used in Tunisian traditional medicine, especially patients with cancer. The current paper highlights, for the first time, the pro-apoptotic properties of its aqueous and ethanolic extracts on leukemic, colon and pancreatic cancers. Furthermore, their anti-inflammatory and antioxidant activities were evaluated. Both extracts phenolic profile’s was assessed by HPLC analysis. A total of eight and seven compounds respectively in ethanolic and aqueous extracts, were identified as tyrosol (31.86–50.17
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关键词
Ephedra alata,Antioxidant,Anti-inflammatory,Pro-apoptotic,Flow Cytometry,Hematopoietic Monocytic THP-1,Colon Carcinoma SW-620,Pancreatic Carcinoma AsPC-1
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