Viscoelastic blood coagulation testing system enabled by a non-contact triboelectric angle sensor

Thromboelastography (TEG) remains a convenient and effective viscoelastic blood coagulation testing device for guiding blood component transfusion and assessing the risk of thrombosis. Here, a TEG enabled by a non-contact triboelectric angle sensor (NTAS) with a small size (similar to 7 cm3) is developed for assessing the blood coagulation system. With the assistance of a superelastic torsion wire structure, the NTAS-TEG realizes the detection of blood viscoelasticity. Benefiting from a grating and convex design, the NTAS holds a collection of compelling features, including accurate detection of rotation angles from -2.5 degrees to 2.5 degrees, high linearity (R2 = 0.999), and a resolution of 0.01 degrees. Besides, the NTAS exhibits merits of low cost and simplified fabrication. Based on the NTAS-TEG, a viscoelastic blood coagulation detection and analysis system is successfully constructed, which can provide a graph and parameters associated with clot initiation, formation, and stability for clinicians by using 0.36 mL of whole blood. The system not only validates the feasibility of the triboelectric coagulation testing sensor, but also further expands the application of triboelectric sensors in healthcare. Thromboelastography (TEG) remains a convenient and effective viscoelastic coagulation testing device. This paper presents a novel TEG enabled by a miniaturized triboelectric coagulation sensor, which can realize a comprehensive assessment of the coagulation system and is expected to promote the miniaturization of traditional TEGs. image