Closed genome sequence of Clostridium botulinum type B1 strain isolated from an infant botulism case in the United States

Christine A. Pillai,Nagarajan Thirunavukkarasu,Narjol Gonzalez-Escalona,David Melka,Phillip Curry,Rachel Binet,Sandra Tallent,Eric Brown,Shashi Sharma

MICROBIOLOGY RESOURCE ANNOUNCEMENTS（2024）

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摘要

We present the closed genome sequence of the Clostridium botulinum BT-22100019 strain isolated from the stool specimen of an infant diagnosed with botulism. With 4.33-Mb genome size and 28.0% G + C content, the bont/B1 gene encoded for botulinum neurotoxin serotype B was found on a 262 kb plasmid arranged in a ha+ orfx - cluster.

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关键词

Clostridium botulinum,short-read sequencing,MiSeq,illumina,minion,nanopore,genomic characterization,infant botulism

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