Overview of Updates in New The Bethesda System for Reporting of Thyroid Cytopathology Using the Latest World Health Organization Thyroid Tumor Classification Terminology

The new World Health Organization (WHO) thyroid tumor classification employs a histopathology and molecular-based approach to group thyroid tumors aligned with their clinical risk-based management.( 1 Baloch Z.W. Asa S.L. Barletta J.A. Ghossein R.A. Juhlin C.C. Jung C.K. LiVolsi V.A. Papotti M.G. Sobrinho-Simoes M. Tallini G. Mete O. Overview of the 2022 WHO classification of thyroid neoplasms. Endocrine pathology. 2022 Mar; 33: 27-63 Crossref PubMed Scopus (168) Google Scholar , 2 Rossi ED, Baloch Z. The Impact of the 2022 WHO Classification of Thyroid Neoplasms on Everyday Practice of Cytopathology. Endocrine Pathology. 2023 Feb 17:1-1. Google Scholar ) The third edition of The Bethesda System for Reporting of Thyroid Cytopathology(TBSRTC) focuses on incorporating these changes, adoption of new terminologies and allowing application of TBSRTC in paediatric thyroid nodules.( 3 Han M. Fan F. Bethesda System for Reporting Thyroid Cytopathology–An Updated Review. Journal of Clinical and Translational Pathology. 2023 Apr 22; : 1-15 Google Scholar , 4 Ali SZ, VanderLaan PA. The Bethesda System for Reporting Thyroid Cytopathology. Definitions, Criteria, and Explanatory Notes, 3rd ed. New York, NY : Springer; 2023. Google Scholar , 5 Syed Z. Ali, Zubair W. Baloch, Beatrix Cochand-Priollet, Fernando C. Schmitt, Philippe Vielh, and Paul A. VanderLaan.The 2023 Bethesda System for Reporting Thyroid Cytopathology. Thyroid. ahead of print. http://doi.org/10.1089/thy.2023.0141 Google Scholar ) In this brief review, we intend to highlight the updates in both these thyroid systems with special emphasis on the changes in the new TBSRTC for practicing thyroid cytopathologists. This system has six categories with a simple unified label for each category with clearly stated diagnostic criteria.