The use of machine perfusion in surgical oncology and split liver transplantation

Hepatobiliary surgical oncology and liver transplantation (LT) surgery have mutually benefited from their technological progresses and technical achievements of the last decade. The application of machine perfusion (MP) to ex-situ hepatectomies allows more patients with primary unresectable tumours to have access to radical treatment. Furthermore, the growing need for liver grafts for transplant purpose engaged surgeons in finding new solutions such as liver splitting during dynamic storage through MP to preserve the possibility of two LTs when in-situ splitting is not feasible.