Ultra‐Fast Photonic Digital Polymerase Chain Reaction based on N‐Heterocyclic Carbene Self‐Assembled Monolayer (Adv. Funct. Mater. 37/2023)

Photonic Digital PCR In article number 2303728, Sang Hun Lee, Oh Seok Kwon, and co-workers introduce a novel interfacial chemical, N-Heterocyclic Carbene (NHC), for binding stability between Au and the anti-quenching layer under high-temperature based on the self-assembled monolayer. This technology overcomes the limitation of quenching issues in the plasmonic-based digital polymerase chain reaction (dPCR) field. The novel interfacial chemical-based photonic dPCR is promising for applications in the next PCR system and the molecular diagnosis field.