The Data and Safety Monitoring Board: The Toughest Job in Clinical Trials.
NEJM evidence（2023）
摘要
The DSMB: The Toughest Job in Clinical TrialsIn this review article, the authors discuss methods that DSMBs can use to compare the absolute and relative risks of benefits and adverse effects between trial interventions and illustrate how the DSMB can use this approach to evaluate the balance of these competing risks. Two approaches are discussed - the win ratio and the DOOR probability on one treatment relative to another.
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关键词
safety monitoring board,clinical trials,data
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