Insights from the tubal transcriptome on carcinogenesis in hereditary ovarian cancer: A single-cell RNA sequencing analysis

David Samuel,Isabella Allen,Destiny Burnett,Melissa Castillo,Alyssa Mercadel,Alex Sanchez-Covarrubias,Andre Pinto,Patricia Jeudin,Abdulrahman Sinno,Matt Pearson,Marilyn Huang,Matthew Schlumbrecht,Sophia George

GYNECOLOGIC ONCOLOGY（2023）

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摘要

To identify tubal single-cell transcriptional networks related to carcinogenesis in women with different germline homologous recombination (HR) DNA repair mutations at risk for high-grade serous ovarian carcinoma (HGSOC).

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关键词

hereditary ovarian cancer,tubal transcriptome,ovarian cancer,rna,single-cell

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