Impact of COVID ‐19 on the management and outcomes of ureteric stones in the UK : a multicentre retrospective study

Matthew H.V. Byrne,Fanourios Georgiades,Alexander Light,Catherine E. Lovegrove,Catherine Dominic, Josephine Rahman, Senthooran Kathiravelupillai,Tobias Klatte,Kasra Saeb‐Parsy,Rajeev Kumar,Sarah Howles,Grant D. Stewart,Ben Turney,Oliver Wiseman, Ismail Mokadem,Nikolaos Kostakopoulos, Georgios Kounidas, Niyukta Thakare,Andre Chu Qiao Lo, Islam Abu‐Nayla, Ibifuro Dokubo, Marios Ghobrial,Nimlan Shanmugathas, Rama Jha, Roma Thakker,Ranan Dasgupta, Aleksandra Dunin‐Borkowska, Mahmoud Nosseir,Michael Young, Laura McAuley, Ravkaranvir Singh Dharni, Jay Atkinson, Andrew Dickinson, Selene Basso,John Pascoe, Katrina Paton, Abyrami Sivanandarajah, Tessa Stewart, Rosie Johnson,Charles Horn, Adeyinka Laoye, Aron Thomas, Twakondwa Machina, George Neelankavil Davis, Felicite Mukeshimana, Theodora Chatzimichail, Anuj Gupta,Hytham K S Hamid,Stephen Gordon, Faiz Shaikh, Oliver Bottrell, Jacquelina Chui, James Prentice, Natalie George, Rajan Veeratterapillay,Robert Geraghty, Alistair Rogers, Matthew Shaw, Kim Davenport, Julian Peacock, Ayah Atiyah, Zeid Atiyah, Erfan Masiha, Susan Willis, Anoushka Ramkumar, Maitrey Darrad, Chaitya Desai, Shreya Bhatt, Vinura Munasinghe, Georgios Karagiannidis, Helen Wei Cui, William Wong, Remarez Sheehan, Nayanika Sreejith,Benjamin Turney, Alisha Kanani, Paul Armitage, Jemini Vyas, Oluwabukola Olaitan, Jerry Raju, Narin Suleyman, John Bycroft, Gita Lingam, Darryl Bernstein, Vashist Motkur, Laura Derbyshire, Sinthuja Naguleswaran, Ben Robin Grey, Omar Haque, Lahiru Siriwardena, David Muthuveloe, Munira Mohamud, Suprateeka Talukder, Stuart Irving, Sumbal Bhatti, Louisa Sowah Quarshie, Dhaval Bodiwala, George Davies, Thomas Joy, Benjamin Langhorne, Rakan Odeh, Nicholas Boxall, Emmanuel Okpii, Hui Ping Lee, Kesavapilla Subramonian, Prashanthan Balendran, Emily Warmington, Rereloluwa Babalola, Matthew Liew, Sean Rezvani, Matt Clark, Johanna Thomas,Catherine E Lovegrove, Emily Crawley, Anna Sozanska, Holly Thompson, Silvian Tan, Irena Shiderova,Emily Burns, Shalom Srirangam, Luke Hanna,Rotimi David, Oliver Hald, Tommy Johnston, Yih Chyn Phan, Nikos Tteralli,Bogdan Toia, Hadi Mohsin, Xinting Liu, Olivia Creswell, Thomas Fonseka, Lucy Tuckwood, Giacomo Caddeo, Lynsey Harrower, Alysha Careless, Yusuf Sarwar, Aris Alexiadis, Khalid Bukhashem, Jacob Mark Patterson, Samantha Conroy, Hannah Pendegast, Areej Paracha, Lynsey McHugh, Parthvi Vanalia,Nikhil Nandan Mayor, Jamal Dirie,Hugh Mostafid, Elizabeth Brewin, Bhaskar Somani, Mriganka Sinha, Brett Dawson, Marco Bolgeri,Emily Tsang, Nikolaos Sourkounis, Ivana Homerova, Firas Nasr,Abisola Oliyide, Adebanji Adeyoju, Ijeoma Chibuzo, Charlotte Roberts, Zara Jemima Gall, Angus Chin On Luk, Ricardo Fernandes, Charlotte Whitton, Maria Ahmad, Adam Hinchcliffe,Hrishi Joshi,Setthasorn Ooi, Abdullah Almitwalli, Matthew Trail, Feras Al Jaafari, Slawomir Grzegorz Kata, Yasser Elsayed, Stuart James Graham, Martina Spazzapan, Pallavi Olivia Pal, Amarjit Bdesha, Edward Armstrong,Sarah Howles, Mariam Koronfel, Simon Huf, Zakir Hussain, Jamiu Hassan, Olajide Ayomide, Kai Chi Chan,

BJU International(2022)

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摘要
To determine if management of ureteric stones in the UK changed during the coronavirus disease 2019 (COVID-19) pandemic and whether this affected patient outcomes.We conducted a multicentre retrospective study of adults with computed tomography-confirmed ureteric stone disease at 39 UK hospitals during a pre-pandemic period (23/3/2019-22/6/2019) and a period during the pandemic (the 3-month period after the first severe acute respiratory syndrome coronavirus-2 case at individual sites). The primary outcome was success of primary treatment modality, defined as no further treatment required for the index ureteric stone. Our study protocol was published prior to data collection.A total of 3735 patients were included (pre-pandemic 1956 patients; pandemic 1779 patients). Stone size was similar between groups (P > 0.05). During the pandemic, patients had lower hospital admission rates (pre-pandemic 54.0% vs pandemic 46.5%, P < 0.001), shorter mean length of stay (4.1 vs 3.3 days, P = 0.02), and higher rates of use of medical expulsive therapy (17.4% vs 25.4%, P < 0.001). In patients who received interventional management (pre-pandemic 787 vs pandemic 685), rates of extracorporeal shockwave lithotripsy (22.7% vs 34.1%, P < 0.001) and nephrostomy were higher (7.1% vs 10.5%, P = 0.03); and rates of ureteroscopy (57.2% vs 47.5%, P < 0.001), stent insertion (68.4% vs 54.6%, P < 0.001), and general anaesthetic (92.2% vs 76.2%, P < 0.001) were lower. There was no difference in success of primary treatment modality between patient cohorts (pre-pandemic 73.8% vs pandemic 76.1%, P = 0.11), nor when patients were stratified by treatment modality or stone size. Rates of operative complications, 30-day mortality, and re-admission and renal function at 6 months did not differ between the data collection periods.During the COVID-19 pandemic, there were lower admission rates and fewer invasive procedures performed. Despite this, there were no differences in treatment success or outcomes. Our findings indicate that clinicians can safely adopt management strategies developed during the pandemic to treat more patients conservatively and in the community.
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ureteric stones
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