Bevacizumab in the Treatment of Refractory Brain Edema in High-grade Glioma

Aysha K. Alsahlawi, Claudie Michaud-Couture,Alexandre Lachance, Samuel Bergeron-Gravel, Melanie Letourneau, Catherine Bourget, Peter V. Gould, Panagiota Giannakouros, Emily M. Nakada,Damien Faury,Louis Crevier,Eric Bouffet,Nada Jabado,Valerie Larouche,Samuele Renzi

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY（2024）

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摘要

We report the case of a 14-year-old boy with a steroid-dependent refractory tumor whose longstanding dexamethasone treatment was successfully discontinued after a course of bevacizumab. The use of bevacizumab despite the absence of clear evidence of radionecrosis allowed a significant decrease in the amount of the brain edema.

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vasogenic brain edema,bevacizumab,dexamethasone,gliomas,oncology

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