Prefrontal cortex signals value category while basal ganglia represent learned values in value learning
biorxiv(2023)
摘要
Value learning can be variable for objects with the exact same reward but the underlying neural mechanism for such variability is not known. We have addressed this question by recording single-unit activity in the prefrontal cortex (PFC) and substantia nigra reticulata (SNr), two key nodes in cortex-basal ganglia circuitry with crucial roles in value learning, as macaque monkeys learned to associate novel objects with either high or low rewards. Estimating the trial by trial learned values based on choice performance, revealed stark differences between learned values across objects with the same reward outcome. Importantly, while PFC neurons rapidly learned to differentiate objects based on their value category, the firing in SNr correlated with the variability in learned values within a value category. Our results suggest that the variation in objects learned values is more likely to be a readout of SNr firing while PFC may provide a top-down teaching signal to basal ganglia to demarcate the value categories.
### Competing Interest Statement
The authors have declared no competing interest.
更多查看译文
关键词
basal ganglia,cortex,values
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要