Combinatorial Synthesis of Indole Derivatives as Anti-oomycetes Agents.

Fei Hai,Ruxue Wei,Yan Li, Ruiguang Wang,Yuee Tian,Shengming Liu,Genqiang Chen,Zhiping Che

Combinatorial chemistry & high throughput screening（2023）

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摘要

The preliminary structure-activity relationship showed that the formyl group modification at the C-3 position of the indole ring was acceptable, and the different anti-oomycete activities of R1 and R2 were significantly different, with R1 being 5-CN > H > 6-Me, and R2 being 4-NO2 > 3-NO2, H > 4-Me.

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