Gender Differences of Gly972Arg Polymorphism of the IRS-1 Gene Related to Cardiovascular Disease Risk Factors Among Indonesians.

Renan Sukmawan, Harry Mahathir Akip, Priyandini Wulandari, Evans T Bobians, Brm Ario Soeryo Koencoro,Siska Suridanda Danny,Ade Meidian Ambari,Sunu Budhi Raharjo,Bambang Widyantoro,Suko Adiarto

Acta medica Indonesiana（2023）

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摘要

There were a higher proportion of women than men carrying the T allele of Gly972Arg polymorphism among Indonesians. Individuals with the T allele appeared to show a greater prevalence of hypertension. These results may explain a possible mechanism of the high prevalence of metabolic syndrome in Indonesia, especially in women.

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gender,gly972arg polymorphism,irs-1 gene,indonesian

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