Concerns about aortic aneurysm or dissection risk should not cease fluoroquinolone use when clinically indicated.

Graphical AbstractOpen in new tabDownload slideThere were no differences in the risk of aortic aneurysm and dissection in outpatients treated with oral fluoroquinolones or third-generation cephalosporins. AA/AD: aortic aneurysm/aortic dissection; CI: confidence interval; FQ: fluoroquinolones; 3GC: third generation cephalosporin; IPTW: inverse probability of treatment weighting; PS: propensity score.