Evaluation of miRNA-200c and βIII tubulin as promising markers for clinical decision making in locally advanced breast cancer patients receiving taxanes therapy

Fatma M. Abdelwahed,Nadia I. Zakhary,Rasha M. Allam,Amany A. Abou-Bakr,Saad M. El-Gendy,Alfred E. Namour

Gene Reports（2023）

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摘要

•The miRNA-200c and βIII tubulin are promising markers for clinical decision making in LABC patients.•The miRNA-200c may be a predictive marker for response to neoadjuvant taxanes therapy in breast cancer patients.•The βIII tubulin protein showed association with ER and PR status of breast cancer patients.•The βIII tubulin protein demonstrates an association with molecular subtypes of breast cancer

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关键词

Advanced breast cancer, miRNA 200c, ss III tubulin, Luminal, Non luminal, Response

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