The safety and efficacy of total mesorectal excision (TME) surgery following dose-escalation: Surgical outcomes from the organ preservation in early rectal adenocarcinoma (OPERA) trial, a European multicentre phase 3 randomised trial (NCT02505750).
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland（2023）
摘要
Dose escalation can facilitate nonsurgical treatment for cT2-3 rectal cancer patients who are fit but wish to avoid TME surgery and stoma. If TME surgery is required, then it can be performed safely and effectively.
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关键词
contact X-ray brachytherapy, neoadjuvant treatment, organ preservation, rectal cancer
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