Correlation between B cell epitope profile and clinical features of anti-MDA5 antibody-positive dermatomyositis.

Koichi Yamaguchi,Paul Poland,Tissa Bijoy George,Didem Saygin,Siamak Moghadam-Kia,Rohit Aggarwal,Chester V Oddis,Lei Zhu,Dana P Ascherman

Rheumatology (Oxford, England)（2023）

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摘要

Various clinical features of MDA5+ dermatomyositis correlated with levels of antibodies targeting selected subfragments of this autoantigen, providing a link between fragment-specific immune responses and disease course.

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关键词

myositis, anti-melanoma differentiation-associated gene 5 antibody, fragment, epitope

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