Transcriptome-based analysis of human peripheral blood reveals regulators of immune response in different viral infections.

Frontiers in immunology(2023)

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摘要
The identified relationships between some of them and virus-induced alteration of immune functions are new and have not been found earlier, e.g., receptors for autocrine motility factor, insulin, prolactin, angiotensin II, and immunoglobulin epsilon. Modulation of the identified receptors can be investigated as one of therapeutic strategies for the treatment of severe viral infections.
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关键词
viral infections, transcriptomics, immune response, master regulators, peripheral blood mononuclear cells, COVID-19
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