The Prognostic and Predictive Value of Pre-Treatment Total Lymphocyte Count in HPV+ Oropharyngeal Carcinoma Receiving Definitive (Chemo-) Radiation

C. Johnny,S.H. Huang, J. Su,S. Bratman,J. Cho,E. Hahn,A. Hosni,A. Hope,J. Kim, B. O'Sullivan, J.G. Ringash,J. Waldron, A. Spreafico,L. Eng,D. Goldstein,L. Tong, W. Xu,A. McPartlin

International journal of radiation oncology, biology, physics（2023）

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摘要

Pre-treatment TLC is prognostic in a large cohort of HPV+OPC patients receiving CRT but not RT alone. Further investigation of the interaction of cisplatin and immune response during RT is warranted. The omission of chemotherapy based on TLC is not supported.

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carcinoma,radiation,pre-treatment

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