Differential effects of selective versus unselective sphingosine 1-phosphate receptor modulators on T- and B-cell response to SARS-CoV-2 vaccination.

Undine Proschmann,Magdalena Mueller-Enz,Christina Woopen,Georges Katoul Al Rahbani,Rocco Haase,Anja Dillenseger,Marie Dunsche,Yassin Atta,Tjalf Ziemssen,Katja Akgün

Multiple sclerosis (Houndmills, Basingstoke, England)（2023）

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摘要

Our data confirm differential effects of selective versus unselective S1PRMs on T- and B-cell response to SARS-CoV-2 vaccination and suggest association with S1PRM selectivity rather than lymphocyte redistribution.

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关键词

Multiple sclerosis, sphingosine 1-phosphate receptor modulators, disease-modifying therapies, T-cell response, B-cell response, SARS-CoV-2 vaccination

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