White Matter Tract Density Index Prediction Model of Overall Survival in Glioblastoma.

Alessandro Salvalaggio,Lorenzo Pini,Matteo Gaiola,Aron Velco,Giulio Sansone,Mariagiulia Anglani,Lucius Fekonja,Franco Chioffi,Thomas Picht,Michel Thiebaut de Schotten,Vittorina Zagonel,Giuseppe Lombardi,Domenico D'Avella,Maurizio Corbetta

JAMA neurology（2023）

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摘要

In this study, GBMs encompassing regions with low white matter tract density were associated with longer OS. These findings indicate that the TDI is a reliable presurgical outcome predictor that may be considered in clinical trials and clinical practice. These findings support a framework in which the outcome of GBM depends on the patient's brain organization.

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