Glycosylation-Engineered Platelet Membrane-Coated Interleukin 10 Nanoparticles for Targeted Inhibition of Vascular Restenosis.

Fengshi Li,Zhihua Rong, Tianqi Chen,Peng Wang,Xiao Di,Leng Ni,Changwei Liu

International journal of nanomedicine（2023）

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摘要

IL10-GE-PNPs emerged as a promising candidate for targeting vascular injury and exhibited potential as an innovative drug delivery system for suppressing vascular restenosis. The engineered glycosylation of IL10-PNPs improved their immune compatibility and targeting abilities, making them an excellent therapeutic option.

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关键词

vascular restenosis, platelet membrane, glycosylation, interleukin 10, targeting delivery

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