Low Alanine Aminotransferase, as a Marker of Sarcopenia and Frailty, Is Associated with Shorter Survival Among Prostate Cancer Patients and Survivors. A Retrospective Cohort Analysis of 4064 Patients

Menachem Laufer, Maxim Perelman, Michal Sarfaty,Edward Itelman,Gad Segal

European Urology Open Science（2023）

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摘要

In the current era of advanced precision medicine, there is a place for better-personalized treatment strategies, especially for elderly patients. We found that low alanine aminotransferase (ALT), indicative of sarcopenia and frailty, was associated with shorter survival for prostate cancer patients and survivors. ALT measurement at baseline could guide treatment decisions in this patient population.

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关键词

Prostate cancer, Sarcopenia, Frailty, Alanine aminotransferase, Survival, Prostate-specific antigen

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