Cortical and subcortical morphometric changes and their relation to cognitive impairment in isolated REM sleep behavior disorder.

Christiane Mala,Filip Havlík,Josef Mana,Jiří Nepožitek,Simona Dostálová,Evžen Růžička,Karel Šonka,Jiří Keller,Robert Jech,Petr Dušek,Ondrej Bezdicek,Radim Krupička

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology（2023）

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摘要

iRBD shows deficits in several cognitive tests that correlate with morphological changes, the most prominent of which is in psychomotor speed and visual attention as measured by the TMT-A and associated with the volume of striatum, insula, cerebellum, temporal lobe, pallidum and amygdala.

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关键词

Mild cognitive impairment,Prodromal,Synucleinopathy,Cognition,Trail Making Test,REM sleep without atonia

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