Dermatology Healthcare Utilization in Solid-Organ Transplant Recipients: A Retrospective Cohort Study.

The Journal of investigative dermatology(2023)

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摘要
Solid organ transplant recipients (SOTRs) are at an elevated risk of developing keratinocyte carcinomas (KCs) and malignant melanomas. Notably, KCs (squamous cell carcinomas [SCCs] and basal cell carcinomas [BCCs]) comprise 40-50% of all post-transplant neoplasms ( Vajdic and van Leeuwen, 2009 Vajdic C.M. van Leeuwen M.T. Cancer incidence and risk factors after solid organ transplantation. Int J Cancer. 2009; 125: 1747-1754 Crossref PubMed Scopus (317) Google Scholar ). Approximately half of SOTRs with at least 1 posttransplant skin cancer may develop a subsequent skin cancer within 2 years ( Wehner et al., 2021 Wehner M.R. Niu J. Wheless L. Baker L.X. Cohen O.G. Margolis D.J. et al. Risks of Multiple Skin Cancers in Organ Transplant Recipients: A Cohort Study in 2 Administrative Data Sets. JAMA Dermatol. 2021; 157: 1447-1455 Crossref PubMed Scopus (5) Google Scholar ). To date, research has focused on the epidemiology and risk factors associated with post-transplant skin cancers, however, there is a limited understanding of the dermatological healthcare utilization among SOTRs, including skin cancer surveillance visits, biopsies, and actinic keratosis treatments, in addition to skin cancer treatments. We sought to describe the dermatological healthcare utilization and burden among SOTRs.
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