P12-A107 Porcine cornea ex vivo model as an alternative to human donor tissues for investigating new preservation conditions.

Umberto Rodella, Lorenzo Bosio,Stefano Ferrari, Claudio Gatto, Laura Giurgola, Orietta Rossi,Stefano Ciciliot,Eugenio Ragazzi,Diego Ponzin,Jana D'Amato Tóthová

BMJ open ophthalmology(2023)

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摘要
The presented porcine cornea model represents a reliable and alternative model to human donor tissues for preliminary investigations and can be used for testing new media, substances, drugs, or preservation conditions and their impact on corneal tissue quality and safety. Furthermore, the quantitative method to assess whole endothelium mortality can be implemented at eye banks for the evaluation of corneas intended for transplantation.
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