Evaluating the causal effect of circulating proteome on the risk of osteoarthritis-related traits.

Yan Zhang,Jingyu Xie,Simin Wen,Peihua Cao,Wende Xiao,Jianwei Zhu,Shengfa Li,Zhiqiang Wang,Han Cen,Zhaohua Zhu,Changhai Ding,Guangfeng Ruan

Annals of the rheumatic diseases（2023）

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摘要

Through MR analysis, we have identified numerous plasma proteins associated with OA-related traits, shedding light on protein-mediated mechanisms and offering promising therapeutic targets for OA.

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关键词

Epidemiology, Osteoarthritis, Polymorphism, Genetic, Cytokines

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