Altered frequency of FOXP3 + regulatory T cells is associated with development of inhibitors in patients with severe hemophilia A.

Nargess Arandi,Omid Reza Zekavat,Negin Shokrgozar,Amin Shahsavani,Hossein Golmoghaddam,Mehdi Kalani

International journal of laboratory hematology（2023）

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摘要

Our data demonstrated for the first time that the CD4 CD25 FOXP3 Tregs might be implicated in the prevention of inhibitor formation in severe HA patients.

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关键词

Factor VIII (FVIII), FOXP3, inhibitors, regulatory T cells (Tregs), severe hemophilia A (HA)

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