Molecular profiling of solid tumors by next-generation sequencing: an experience from a clinical laboratory.

Pratibha Bhai,Jacob Turowec,Stephanie Santos,Jennifer Kerkhof,LeeAnne Pickard,Aidin Foroutan,Daniel Breadner,Matthew Cecchini,Michael A Levy,Alan Stuart,Stephen Welch,Christopher Howlett,Hanxin Lin,Bekim Sadikovic

Frontiers in oncology（2023）

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摘要

The findings of our study demonstrate the feasibility of integrating an NGS-based gene panel screen as part of a standard diagnostic protocol for solid tumor assessment. High diagnostic rates enable significant clinical impact including improved diagnosis, prognosis, and clinical management in patients with solid tumors.

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molecular profiling,solid tumors,next-generation

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