Smyd2 As A New Therapeutic Target For Hepatocellular Carcinoma

Bárbara Bueloni,Esteban Fiore, MariaJose Cantero, Luciana Dominguez,Catalina Atorrasagasti,Mariana Garcı́a, JuanMiguelBayo Fina,Guillermo Mazzolini

Zeitschrift Fur Gastroenterologie（2023）

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摘要

Introduction The development of new treatments for advanced hepatocellular carcinoma (HCC) remains urgent due to the limited impact of available therapies patient survival. The methyltransferase SMYD2 acts as an oncogene in numerous types of cancers, but its involvement in HCC remains elusive. Thus, we aimed to assess the therapeutic potential of SMYD2 pharmacological inhibition in HCC.

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关键词

smyd2,hepatocellular carcinoma,new therapeutic target

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