Gene Signatures for Latent Radiation-Induced Lung Injury Post X-ray Exposure in Mouse.

Tongtong Zhang,Zhaoming Zhou,Lei Wen,Changguo Shan,Mingyao Lai, Jing Liao,Xin Zeng,Gang Yan,Linbo Cai,Meijuan Zhou, Minghua Wang

Dose-response : a publication of International Hormesis Society（2023）

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摘要

Our research determined the X-ray-specific sensitive gene set in mice lungs after exposure to radiation. The gene set could be used as a genetic marker to suggest the latency of RILI. The enrichment analysis results suggested that the relevant signaling pathways were potentially involved in the development of RILI. Further validation of those genes and signaling pathways is needed to confirm these findings.

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lung,gene,radiation-induced,x-ray

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