MK2 drives progression of pancreas and colon cancers by suppressing CD8 + T cell cytotoxic function and is a potential immunotherapy target.

Damian Jacenik, Eric J Lebish,Ellen J Beswick

Frontiers in immunology（2023）

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摘要

Overall, we documented that MK2 drives the progression of gastrointestinal cancers and prevents immune response generated by CD8 T cells suggesting potential implications of MK2 in the immunotherapy of gastrointestinal cancers.

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关键词

colon cancers,pancreas,potential immunotherapy target

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