Causal Association Between mTOR-Dependent Protein Levels and Alzheimer's Disease: A Mendelian Randomization Study.

Hong-Yan Cai,Si-Jia Hou, Rui Wen, Qi-Fan Feng,Yu-Jia Xi,Sheng-Xiao Zhang,Jun Qiao,Mei-Na Wu

Journal of Alzheimer's disease : JAD（2023）

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摘要

There was a causal relationship between the mTOR signaling and the risk for AD. Activating AKT and RP-S6K, or inhibiting eIF4E may be potentially beneficial to the prevention and treatment of AD.

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关键词

Alzheimer's disease, causal relationships, mammalian target of rapamycin, Mendelian randomization

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