Vancomycin population pharmacokinetics analysis in Chinese paediatric patients with varying degrees of renal function and ages: development of new practical dosing recommendations.

Jihui Chen,Xiaohui Huang, Liting Yu,Jiru Li, Rui Yang,Lixia Li,Jia Zhou,Huijuan Yao,Shuhong Bu

The Journal of antimicrobial chemotherapy（2023）

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摘要

We established vancomycin pharmacokinetic parameters in Chinese paediatric patients and proposed a dosing guideline integrating eGFR, age and CTS status, potentially improving clinical outcomes and reducing nephrotoxicity risk.

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关键词

population pharmacokinetics,chinese paediatric patients,paediatric patients,renal function

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